Anisocoria is defined by a difference in 1mm in absolute value of the pupil’s diameter. 50% of episodes of anisocoria could not be diagnosed by a trained nurses staff but only with pupillometry. Pupillometry could present a diagnostic interest and allow an earlier and more reliable detection of anisocoria. An earlier diagnosis of anisocoria could allow an prompter care such as the medico-surgical release of raised intracranial pressure and improve patient’s outcome.

Crit Care. 2016 Mar 13;20:99. doi: 10.1186/s13054-016-1239-z.

Reliability of standard pupillometry practice in neurocritical care: an observational, double-blinded study.

Couret D^1,2, Boumaza D³, Grisotto C¹, Triglia T³, Pellegrini L³, Ocquidant P¹, Bruder NJ³, Velly LJ⁴.

Pupillometry offers also quantitative non-invasive measure of the sympathovagal balance basal state and reactivity through the patented NeuroPupillar Index® or the percent dilation changes. In brain trauma pupillometry, these could help diagnose or predict raised ICP or present an early prognostic value in post-anoxic coma. Further studies are required to define the role for automated pupillomatry in usual care.